Squamous Cell Carcinoma on Seborrheic Keratosis

[Squamous cell carcinoma on seborrheic keratosis].

To the Editor: Seborrheic keratosis is one of the most common benign epidermal tumors in dermatologic clinical practice. Although the association between seborrheic keratosis and other skin tumors was first reported in 1932, its malignant transformation is very rare, with less than 20 published cases. We present the case of a patient with seborrheic keratosis that underwent transformation into ...

Actinic Keratosis and Squamous Cell Carcinoma

Actinic keratosis and squamous cell carcinoma.

Actinic keratosis is a common skin disorder in elderly patients with fair complexions. It is caused by exposure to ultraviolet light. If left untreated, actinic keratosis may progress to squamous cell carcinoma. The metastatic potential and prognosis vary with the type and location of the lesion. Several approaches to treatment are available, including local destruction, excisional surgery, Moh...

Actinic Keratosis and Squamous Cell Carcinoma

An overview of Bcl-2 expression in histopathological variants of basal cell carcinoma, squamous cell carcinoma, actinic keratosis and seborrheic keratosis.

The Bcl-2 protein has been shown to suppress cell death and protects cell against apoptosis induced by different death-inducing signals. In this study the authors have analyzed imunohistochemically the expression of Bcl-2 protein in the histopathological variants of the most common malignant tumors of the skin--basal cell carcinoma (BCC) and squamous cell tumor (SCC), as well as in the precance...